Twisting and Stretching
Single Molecules
Adding a twist to DNA
1 List
1Supported membranes: Scientific and practical applications
E. Sackmann, (sackmann@ph.tum.de )
Science (1996-01-05) 271-5245 p.43 Science publications
Publisher : AMER ASSOC ADVANCEMENT SCIENCE, 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005 USA. ISSN : 0036-8075
Abstract : Scientific and practical applications of supported lipid-protein bilayers are described. Membranes can be covalently coupled to or separated from solids by ultrathin layers of water or soft polymer cushions, The latter systems maintain the structural and dynamic properties of free bilayers, forming a class of models of biomembranes that allow the application of a manifold of surface-sensitive techniques, They form versatile models of low-dimensionality complex fluids, which can be used to study interfacial forces and wetting phenomena, and enable the design of phantom cells to explore the interplay of lock-and-key forces (such as receptor-ligand binding) and universal forces for cell adhesion, Practical applications are the design of (highly selective) receptor surfaces of biosensors on electrooptical devices or the biofunctionalization of inorganic solids.
Corresponding Author : Sackmann, E, TECH UNIV MUNICH,DEPT PHYS E22,BIOPHYS LAB,D-85747 GARCHING,GERMANY.
Key words : LIPID BILAYERS; IMMUNE-SYSTEM; RECOGNITION; MONOLAYERS; SURFACES; LAYERS; CELL; TRANSITIONS; INTERFACE; RESONANCE
Type : Article, English. 1996-01-05
Time cited 548; Journal impact factor for year 1996 equals 23.605
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